AG Scientific/Bafilmycin A1/1 mg/B-1183-1 mg
商品编号：
B-1183-1mg
品牌：
agscientific
市场价：
¥4284.00
美元价：
3213.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Baf-A1; Baf A; Hygrolidin; tetraen-2-one
SKU
B-1183
CAS #
88899-55-2
Chemical Name
(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one
Chemical Formula
C35H58O9
Molecular Weight
622.8 Da
Appearance
White solid
Purity
>95% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. DMSO @ 50mg/ml. Poor water solubility.
Melting Point
N/A
Preparation
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Bafilomycin A1 inhibit macroautophagy and promote apoptosis in colon cancer cells. Baf A1 inhibits the action of Tentanus toxin in spinal cord neurons in cell culture. It also inhibits rhinovirus infection in human airways.
Merck Index
N/A
MDL NUMBER
MFCD06795130
CHEMACX
X1087211-6
INCHI
InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3/b14-12+,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33+,35+/m0/s1
SMILES
C[C@H]1C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)O)O)OC)/C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #"S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Warning; Toxic. May be Carcinogenic. Ensure adequate ventilation, especially in confined areas. Use personal protective equipment as required. Use with local exhaust ventilation. Do not breathe dust/fume/gas/mist/vapors/spray.
Key Words
Bafilomycin A1 , Mitochondrial uncoupling, neuronal cells, V-ATPase
msds 1
B-1183, BAFILOMYCIN A1, SDS, diamond format.pdf
Certificate of Analysis 1
B-1183, G1205B.pdf
Certificate of Analysis 2
B-1183, G1205A.pdf
Certificate of Analysis 3
B-1183, G1205.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
