AG Scientific/FK506 (Tacrolimus)/10 mg/F-1030-10 mg
商品编号：
F-1030-10mg
品牌：
agscientific
市场价：
¥1506.00
美元价：
1129.50
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Prograf; Protopic; Fujimycin; Tsukubaenolide; Modigraf; Advagraf; Protopy; Astagraf XL
SKU
F-1030
CAS #
104987-11-3
Chemical Name
(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetron
Chemical Formula
C44H69NO12
Molecular Weight
804.0 Da
Appearance
White powder
Purity
≥99%
Solubility
Clear and colorless at 10 mg/ml DMSO or Ethanol
Melting Point
130-132°C
Storage Temp
-20°C
THERAPEUTIC AREA
Immunotherapy
USE
Tacrolimus, also known as fujimycin or FK506, is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body"s learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema and psoriasis. (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura"s disease, and the skin condition vitiligo.
Merck Index
13.9117.2001
Handling
Avoid contact with skin, eyes, and personal clothing. Wash hands thoroughly after handling. Avoid breathing fumes. Use only with adequate ventilation. Wear suitable protective clothing, gloves, and eye/face protection. Keep away from sources of ignition. Minimize dust generation and accumulation. Keep container tightly closed. Open and handle container with care. Do not eat, drink, or smoke while handling.
msds 1
F-1030, FK-506, SDS, diamond format.pdf
Certificate of Analysis 1
F-1030, G1212A.pdf
Certificate of Analysis 2
F-1030, G1212.pdf
Certificate of Analysis 3
F-1030, F1198E.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
