AG Scientific/Staurosporine/5 mg/S-1016-5 mg
商品编号:
S-1016-5mg
品牌:
agscientific
市场价:
¥9271.60
美元价:
5562.96
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Alternate Name/Synonyms
Antibiotic 230; AM-2282
SKU
S-1016
CAS #
62996-74-1
Chemical Name
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one
Chemical Formula
C28H26N4O3
Molecular Weight
466.5 Da
Appearance
White to yellow powder or lyophilized solid
Purity
≥98%
Solubility
DMSO (50 mg/mL) or ethanol (2 mg/mL, warm).
Melting Point
N/A
Preparation
N/A
Storage Temp
4ºC
THERAPEUTIC AREA
Oncological Disorders
USE
Staurosporine is used to induce cell death in human mesenchymal stem cells and to induce cell death by PKC inhibition in hamster lung fibroblast line CCL-39. When encapsulated in liposome nanoparticle, staurosporine is shown to suppress tumors in vivo in a mouse model without the toxic side effects which have prohibited its use as an anti-cancer drug with high apoptotic activity. Staurosporine is also used to study the effect of caspase activation on human sperm quality.
Merck Index
N/A
MDL NUMBER
MFCD18252446
CHEMACX
X1000602-5
INCHI
InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
SMILES
C[C@@]12[C@@H]([C@@H](C[C@@H](O1)n3c4ccccc4c5c3c6n2c7ccccc7c6c8c5C(=O)NC8)NC)OC
Handling
Wear personal protective equipment. Ensure adequate ventilation. Avoid contact with skin, eyes and clothing. Avoid dust formation. Do not breathe dust. Use only under a chemical fume hood.
Certificate of Analysis 1
S-1016, E1076.pdf
品牌介绍
AG Scientific, Inc.成立于1997年,专注于创新生化制剂以及用于诊断测试开发的定制原材料,以推进临床前研究药物开发。产品涉及抗生素,生物洗涤剂,缓冲液,诊断,酶,医疗设备试剂,蛋白酶K,还原剂,RNase A等。