AG Scientific/Nonactin/50毫克/N-1155-50毫克
商品编号：
N-1155-50mg
品牌：
agscientific
市场价：
¥5610.00
美元价：
3366.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Werramycin-A; Ammonium ionophore; Ammonium ionophore I; Macrotetrolide analogue
SKU
N-1155
CAS #
6833-84-7
Chemical Name
(1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-2,5,11,14,20,23,29,32-octamethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone
Chemical Formula
C40H64O12
Molecular Weight
736.93 Da
Appearance
White powder
Purity
≥95%
Solubility
Soluble in Methanol, Dichloromethane, Ethyl Acetate, DMSO.Insoluble in water.
Melting Point
146°C
Preparation
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Nonactin is a macrotetrolide that forms complexes with alkali cations, such as potassium and sodium. It has been reported to inhibit the processing of cytoplasmic precursor proteins destined for the mitochondria. Nonactin is an uncoupler of oxidative phosphorylation. It has been recorded to function by binding a metal ionophore and transporting it across cell membranes for release. The compound can functionally perform this transport due to its conformational flexibility and hydrophobic exterior. The compound forms a natural diastereomer which is required for its antibacterial and binding capacities.
Merck Index
N/A
MDL NUMBER
MFCD03267283
CHEMACX
X1009767-7
PubChecm ID
72519
INCHI
InChI=1S/C40H64O12/c1-21-17-29-9-13-34(49-29)26(6)38(42)46-23(3)19-31-11-15-36(51-31)28(8)40(44)48-24(4)20-32-12-16-35(52-32)27(7)39(43)47-22(2)18-30-10-14-33(50-30)25(5)37(41)45-21/h21-36H,9-20H2,1-8H3/t21-,22+,23+,24-,25-,26+,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-
SMILES
C[C@@H]1C[C@H]2CC[C@H](O2)[C@@H](C(=O)O[C@H](C[C@@H]3CC[C@@H](O3)[C@H](C(=O)O[C@@H](C[C@H]4CC[C@H](O4)[C@@H](C(=O)O[C@H](C[C@@H]5CC[C@@H](O5)[C@H](C(=O)O1)C)C)C)C)C)C)C
RTECS
RH1685000
Handling
Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
msds 1
N-1155, Nonactin, SDS, diamond format.pdf
Certificate of Analysis 1
N-1155, J1157C.pdf
Certificate of Analysis 2
N-1155, J1157B.pdf
Certificate of Analysis 3
N-1155, J1157A.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
