AG Scientific/ABT-888/A-2178-
商品编号：
A-2178-
品牌：
agscientific
市场价：
¥20.00
美元价：
15.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide dihydrochloride
SKU
A-2178
CAS #
912445-05-7
Chemical Name
2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide . dihydrochloride
Chemical Formula
C13H16N4O.2HCl
Molecular Weight
317.21
Appearance
Coloreless to white crystalline Solid
Purity
98% by HPLC
Solubility
Soluble in DMSO and H2O
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
ABT-888 has been shown to inhibit PARP-1 and PARP-2 for treatment of colon cancer
MDL NUMBER
MFCD12407402
CHEMACX
X1812318-5
INCHI
InChI=1S/C13H16N4O.2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12;;/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17);2*1H/t13-;;/m1../s1
SMILES
C[C@@]1(CCCN1)c2[nH]c3cccc(c3n2)C(=O)N.Cl.Cl
Handling
Protect from air and moisture
Citations
THIRST AND VOLUME, ELECTROLYTE HOMEOSTASIS:Inhibition of the formation of EETs and 20-HETE with 1-aminobenzotriazole attenuates pressure natriuresisElisabete A. Dos Santos, Annette J. Dahly-Vernon, Kimberly M. Hoagland, and Richard J. RomanAm J Physiol Regulatory Integrative Comp Physiol, Jul 2004; 287: R58 - R68.
Citations_Hyperlink
http://ajpregu.physiology.org/cgi/reprint/287/1/R58
Promo text for AGS discount
N/A
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
