CefsulodinSodiumSaltisathirdgenerationcephalosporinantibiotic.UtilizedinmicroBIOLOGyinCIN(Cefsulodin-Irgasan-Novobiocin)Agar,itisusedfortheselectiveisolationofYersiniaenterocolitic.AlsoCefsulodinchocolatebloodagarisaselectivemediumfortherecoveryofHaemophilusinfluenzaefromtherespiratorysecretionsofpatientswithcysticfibrosis.CINagarwasfirstdescribedbySchiemannasanalternativetoMacConkeyAgarandothercommonlyusedmediaforisolationofYersiniaenterocolitica,acausativeagentofgasteroenteritis. CefsulodinhasanimportantroleinwatertestingwhereitisusedasacontaminationcontrolinhibitinggrowthofunwantedbacteriaotherthanE.Coli.
Application:
Clinical-UsedforthetreatmentofsurgicalinfectionscausedbyPseudomonasaeruginosa.
Labapplication-ComponentofMIAgarusedinwatertestingasacontaminationcontrolthatinhibitsthegrowthofbacteriaotherthanE-Coli.
-UsedinCefsulodin-Irgasan-NovobiocinAgar,aselsectivemediafortheisolationofYersiniaenterocolitic.
-Cefsulodin’s longstandingapplicationidentifyingYersiniaenterocoliticahasapowerfulnewroleinGenomeeditingutilizingthe
CRISPR/Cas9system.
AdditionalInformation
| Synonyms | Sulcephalosporin,Abbott46811,CGP-7174/E,Cefomonil,Monaspor,Pseudomonil,Pseudocef,Pyocefal,Takesulin,Tilmapor,Ulfaret |
|---|---|
| Product# | C-1457 |
| CAS# | 52152-93-9 |
| ChemicalName | SODIUM(6R,7R)-3-[(4-CARBAMOYLPYRIDIN-1-IUM-1-YL)METHYL]-8-OXO-7-[[(2R)-2-PHENYL-2-SULFONATOACETYL]AMINO]-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLATE |
| Formula | C22H19N4NaO8S2Na |
| MW | 554.5 |
| Appearance | YellowishcrystallinePowder |
| Purity | 97%HPLC |
| Solubility | Solubleinwater |
| StorageTemp | -20°C |
| TherapeuticArea | InfectiousDiseases |
| Use | Cefsulodinsodiumsalthydrateisathirdgenerationβ-lactamantibioticandamemberofthecephemssubgroupofantibiotics. |
| MDLNumber | MFCD07793338 |
|---|---|
| ChemACX | X1026792-4 |
| InChI | InChI=1S/C22H20N4O8S2.Na/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12;/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34);/q;+1/p-1/t15-,17-,21-;/m1./s1 |
| SMILES | c1ccc(cc1)[C@H](C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[n+]4ccc(cc4)C(=O)N)C(=O)[O-])S(=O)(=O)[O-].[Na+] |
